Lifestyle behavior interventions for preventing cancer in adults with inherited cancer syndromes: systematic review

Background: The link between lifestyle behaviors and cancer risk is well established, which is important for people with personal/family history or genetic susceptibility. Genetic testing is not sufficient motivation to prompt healthier lifestyle behaviors. This systematic review aims to describe and assess interventions for promoting healthy behaviors in people at high risk of cancer. (2) Methods: The review was performed according to PRISMA guidelines using search terms related to hereditary cancer and health education to identify studies indexed in: CINAHL, MEDLINE, PubMed, Cochrane Library, Scopus, and Joanna Briggs, and published from January 2010 to July 2022. (3) Results: The search yielded 1558 initial records; four randomized controlled trials were eligible. Three included patients with and without a personal history of cancer who were at increased risk of cancer due to inherited cancer syndromes, and one included people undergoing genetic testing due to family history. Interventions targeted diet, physical activity, and alcohol. (4) Conclusions: There is a paucity of research on interventions for promoting healthy lifestyle behaviors in people with a high risk of cancer. Interventions produced positive short-term results, but there was no evidence that behavioral modifications were sustained over time. All healthcare professionals can actively promote healthy behaviors that may prevent cancer

Discovering Conversation Spaces in the Public Discourse of Gender Violence: a Comparative Between Two Different Contexts

A huge factor in gender-based violence is perception and stigma, revealed by public discourse. Topic modelling is useful for discourse analysis and reveals prevalent topics and actors. This study aims to find and compare examples of collectivist and individualist conversation spaces of gendered violence by applying Principal Component Analysis, NGram analysis and word association in two gender violence cases which occured in the different contexts of the Philippines and the United States. The data from the Philippines consist of 2010-2011 articles on the 1991 Vizconde Massacre and the data from the United States consist of 2016-2017 articles from the 2015 Stanford Rape Case. Results show that in both cases’ conversation space there is a focus on institutions involved in the cases that does not really change over time, and a time-dependent conversation space for victims. Even in two different contexts of gender violence, patterns in conversation space appear simila

Oligomerization of amyloid Abeta peptides using hydrogen bonds and hydrophobicity forces

The 16-22 amino acid fragment of the beta-amyloid peptide associated with the Alzheimer's disease, Abeta, is capable of forming amyloid fibrils. Here we study the aggregation mechanism of Abeta(16-22) peptides by unbiased thermodynamic simulations at the atomic level for systems of one, three and six Abeta(16-22) peptides. We find that the isolated Abeta(16-22) peptide is mainly a random coil in the sense that both the alpha-helix and beta-strand contents are low, whereas the three- and six-chain systems form aggregated structures with a high beta-sheet content. Furthermore, in agreement with experiments on Abeta(16-22) fibrils, we find that large parallel beta-sheets are unlikely to form. For the six-chain system, the aggregated structures can have many different shapes, but certain particularly stable shapes can be identified.Comment: 19 pages, 7 figures (to appear in Biophys. J.

Double aluminum recovery and its reuse in wastewater treatment

This work evaluates the use of aluminum contained in the aluminum–polyethylene films as anodic electrodes using the electrocoagulation technique to reduce the pollutant contents of industrial wastewater quickly and effectively. Thermal treatment at 500 °C produces pure aluminum (according to TGA and SEM/EDS analysis) which is used to construct aluminum disks (applying 6 tons/cm2 of pressure). Aluminum disks are used as cathodes and anodes in an electrochemical cell. The current density applied in the recovered Al electrodes was 12 mA cm−2, and the maximum COD reduction of wastewater was 77 % at 25 min of treatment. The color and turbidity reductions are 87 and 90 %, respectively. The resulting sludge of wastewater treatment was thermally treated and a second aluminum recovery was reached; since the organic material present in the sludge was removed by the high temperature, the obtained aluminum was pure enough for its reuse. The use of aluminum–polyethylene films as electrodes in the electrocoagulation process contributes to the pollutant removal without the addition of chemical reagents or changing the pH, so it is both effective and environmentally friendly.UAEM-UNAM CONACY

The acquisition of professional skills through service-learning the development of professional skills in the students of the Degree in Early Childhood Education

This experience raises the potential of Service-Learning as a methodology that favors the development of professional skills in the students of the Degree in Early Childhood Education at SAFA University Center (dependent on the University of Jaen). ICT materials and resources have been developed following Universal Design for Learning which promotes an inclusive education making the curriculum accessible to all. The objectives refer to the understanding of inclusive education in real contexts, the search, selection and development of ICT resources and materials following the UDL perspective, as well as promoting reflection on the role of TEPs to promote inclusive education in preschool classrooms. ApS practices have allowed us to get in touch with the real educational context to be able to adjust the materials and resources to students needs. The e-portfolio has allowed us to evaluate the learning of prospect teachers involved. In conclusion, it is shown that the SL methodology favors inclusive education using ICT resources to break down barriers and offer the opportunity to learn to all students.Esta experiencia plantea la potencialidad del Aprendizaje Servicio como metodología que favorece el desarrollo de competencias profesionales en el alumnado del Grado en Educación Infantil del Centro Universitario SAFA (adscrito a la Universidad de Jaén). Se han elaborado materiales y recursos TIC basándose en el planteamiento del Diseño Universal de Aprendizaje que han posibilitado llevar a cabo una educación inclusiva con niños y niñas de infantil haciendo accesible el currículo a todos y todas. Los objetivos que se plantean hacen referencia a la comprensión de la educación inclusiva en contextos reales, la búsqueda, selección y elaboración de recursos y materiales TIC desde la perspectiva del DUA así como potenciar la reflexión sobre el papel de las TEP para potenciar la educación inclusiva en las aulas de infantil. Las prácticas de ApS han permitido conocer el contexto real para poder ajustar los materiales y recursos a las necesidades del alumnado. El e-portafolio nos ha permitido evaluar los aprendizajes de los estudiantes de Magisterio implicados. En conclusión, se pone de manifiesto que la metodología de ApS favorece la educación inclusiva utilizando los recursos TIC para romper las barreras y ofrecer la oportunidad de aprender a todo el alumnado

1-(2-Chlorobenzyloxy)-3-[1,2,3]triazol-1-yl-propan-2-ol Derivatives: Synthesis, Characterization, and DFT-Based Descriptors Analysis

A novel series of 1-(2-chlorobenzyloxy)-3-[1,2,3]triazol-1-yl-propan-2-ol derivatives was designed and synthesized using copper catalyzed alkyne-azide cycloaddition in the key step. Theoretical investigation of molecular and electronic properties by means of global and local reactivity indexes of the synthetized compounds was carried out, using DFT (Density Functional Theory) at PBEPBE/6-31++G∗∗ levelCONACY

Biodiesel and FAME synthesis assisted by microwaves: homogeneous batch and flow processes

Fatty acids methyl esters (FAME) have been prepared under microwave irradiation, using homogeneous catalysis, either in batch or in a flow system. The quality of the biodiesel obtained has been confirmed by GC analysis of the isolated product. While the initial experiments have been performed in a small scale laboratory batch reactor, the best experiment has been straightforward converted into a stop-flow process, by the use of a microwave flow system. Compared with conventional heating methods, the process using microwaves irradiation proved to be a faster method for alcoholysis of triglycerides with methanol, leading to high yields of FAME